Seriál Craig od potoka pojednává o Craigovi a jeho dvou nejlepších kamarádech, Kelsey a JP. Děti se vydávají na různá dobrodružství do nepokořené předměstské divočiny, která se rozléhá kolem místního potoka. V této dětské utopii různé dětské kmeny vládnou pevnostem či cyklo rampám a vytvářejí osobitou dětskou společnost.
Craig and his two best friends, Kelsey and JP, are always going on adventures in the untamed suburban wilderness known as the Creek - a kid utopia where tribes of children rule over tree forts and bike ramps, making up an entire kid society. Each episode finds the kids either venturing into unexplored areas of the Creek, encountering new Creek Kids, or just getting into trouble at their hang out - the Stump.
Craig and his friends discover a large quantity of bugs and decide to care for them by creating a Bug City. Craig suddenly begins becoming possessive of them due to outside elements, such as Mortimer, terrorizing them and decides to take extra precaution by "protecting" them.
An unusually hot day at the Creek melts all of Kit's ice pops, so Craig helps her find a short cut to her frozen snack supplier before everyone else melts.
It's Halloween at the Creek, and Craig is on a mission to collect as much candy as humanly possible, but a spooky ghoul from the Creek's past threatens his haul.